Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226679 | 0.78 | SMN1; SMN2 (0.43) | PTPRAFDPSSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28054527 | 0.67 | HRH1 (0.48) | PTPRAFDPSSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL231091 | 0.65 | FDPS (0.56) | FDPSSMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL8862529 | 0.64 | CYP1A2 (0.42) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL8862781 | 0.63 | HRH1 (0.44) | FDPSSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL8862654 | 0.63 | FDPS (0.47) | PTPRAFDPSSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6638562 | 0.63 | FDPS (0.54) | PTPRAFDPSSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29380824 | 0.63 | FDPS (0.54) | PTPRAFDPSSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2241279 | 0.63 | FDPS (0.54) | PTPRAFDPSSMN1; SMN2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL8862622 | 0.62 | L3MBTL1 (0.45) | FDPSNPC1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648745-A1 | Arylalkylamine having anticonvulsant and neuroprotective properties | Astra Aktiebolag (SE) | 1995-04-19 | — | — | EP | claimed |