Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.64 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.64 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 9/20 | 0.45 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 8/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 8/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 8/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 8/20 | 0.41 |
| ▸ | MGMT | P16455 | 5/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6-Chloroguanine SCHEMBL9226302 | 0.88 | DPP4 (0.68) | PDPK1GDADPP4CDK2MAP3K5 | |
| 2,6-Diaminopurine SCHEMBL22775220 | 0.81 | PDPK1 (0.60) | PDPK1GDADPP4CDK2MAP3K5 | |
| 2,6-Diaminopurine SCHEMBL24053 | 0.80 | PDPK1 (1.00) | PDPK1GDADPP4CDK2MAP3K5 | |
| Guanine SCHEMBL9220514 | 0.80 | PNP (0.70) | GDADPP4OR51E2PNP | |
| 2,6-Diaminopurine SCHEMBL28206545 | 0.78 | PDPK1 (0.96) | PDPK1GDADPP4CDK2MAP3K5 | |
| 2,6-Diaminopurine SCHEMBL8757979 | 0.78 | PDPK1 (0.96) | PDPK1GDADPP4CDK2MAP3K5 | |
| 2,6-Diaminopurine SCHEMBL27891733 | 0.78 | PDPK1 (0.96) | PDPK1GDADPP4CDK2MAP3K5 | |
| 2,6-Diaminopurine SCHEMBL9220440 | 0.78 | OR51E2 (0.42) | PDPK1GDAOR51E2ADORA2A | |
| 2,6-Diaminopurine SCHEMBL29143272 | 0.77 | PDPK1 (0.92) | PDPK1GDADPP4CDK2MAP3K5 | |
| 2,6-Diaminopurine SCHEMBL9424492 | 0.77 | PDPK1 (0.72) | PDPK1GDADPP4CDK2MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215942-B1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD | ANTIVIRALS INC (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0639582-A2 | Polynucleotide assay reagent and method | ANTIVIRALS INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5217866-A | Polynucleotide assay reagent and method | ANTI-GENE DEVELOPMENT GROUP (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0216860-B1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS | SUMMERTON, James (US) | 1992-10-28 | — | — | EP | disclosed |
| EP-0216860-A4 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS. | SUMMERTON JAMES (US) | 1989-02-22 | — | — | EP | disclosed |
| EP-0215942-A4 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1988-08-23 | — | — | EP | disclosed |
| EP-0216860-A1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS. | SUMMERTON JAMES (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0215942-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1987-04-01 | — | — | EP | disclosed |
| WO-1986005518-A1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS | SUMMERTON JAMES | 1986-09-25 | — | — | WO | disclosed |
| WO-1986005519-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD | SUMMERTON JAMES | 1986-09-25 | — | — | WO | disclosed |