SCHEMBL9220523

SCHEMBL9220523

CC(O)C1=C(F)C(n2cnc3c(N)ncnc32)[C@H](O)[C@H]1O

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AHCY P23526 14/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9220528 1.00 AHCY (0.68) AHCY
SCHEMBL15390402 1.00 AHCY (0.68) AHCY
SCHEMBL9217914 0.86 AHCY (0.65) AHCY
SCHEMBL9217906 0.86 AHCY (0.65) AHCY
SCHEMBL15389855 0.84 ADORA3 (0.53) AHCY
SCHEMBL863521 0.81 AHCY (1.00) AHCY
SCHEMBL1521121 0.79 AHCY (0.82) AHCY
Fluoro-Neplanocin A SCHEMBL9215628 0.79 AHCY (1.00) AHCY
SCHEMBL3793061 0.79 AHCY (0.82) AHCY
SCHEMBL863387 0.79 AHCY (0.82) AHCY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0347852-B1 Novel neplanocin derivatives MERRELL DOW PHARMA (US) 1995-08-23 EP disclosed
EP-0347852-A2 Novel neplanocin derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1989-12-27 EP disclosed