Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220532 | 1.00 | ABCC9 (0.53) | ABCC9KDM4EKCNE1KCNQ1MEN1 | |
| SCHEMBL9212275 | 0.92 | ABCC9 (0.52) | ABCC9KDM4EKCNE1KCNQ1MEN1 | |
| SCHEMBL9214323 | 0.88 | ABCC9 (0.56) | ABCC9KDM4EKCNE1KCNQ1ABCB1 | |
| SCHEMBL9214331 | 0.88 | ABCC9 (0.56) | ABCC9KDM4EKCNE1KCNQ1ABCB1 | |
| SCHEMBL9211412 | 0.85 | ABCC9 (0.61) | ABCC9KDM4EKCNE1KCNQ1ABCB1 | |
| SCHEMBL9211421 | 0.85 | ABCC9 (0.61) | ABCC9KDM4EKCNE1KCNQ1ABCB1 | |
| SCHEMBL9211433 | 0.85 | ABCC9 (0.61) | ABCC9KDM4EKCNE1KCNQ1ABCB1 | |
| SCHEMBL9216472 | 0.85 | ABCC9 (0.53) | ABCC9KDM4EABCB1 | |
| SCHEMBL9213480 | 0.85 | ABCB1 (0.54) | ABCC9KDM4EABCB1 | |
| SCHEMBL9213473 | 0.85 | ABCB1 (0.54) | ABCC9KDM4EABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375449-B1 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1995-02-15 | — | — | EP | claimed |
| EP-0375449-A2 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | claimed |
| EP-0375449-B1 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1995-02-15 | — | — | EP | disclosed |
| EP-0375449-A2 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |