Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FABP7 | O15540 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
| ▸ | CCR3 | P51677 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218695 | 0.83 | PTPN1 (0.40) | KMT2AMEN1 | |
| SCHEMBL9213539 | 0.81 | RYR2 (0.47) | — | |
| SCHEMBL9219428 | 0.79 | FABP7 (0.39) | KMT2AKDM4EFABP7FABP5GAA | |
| SCHEMBL9220554 | 0.78 | MALT1 (0.45) | MALT1NOTUMHTR2BHTR2CKDM4E | |
| SCHEMBL9210918 | 0.74 | MALT1 (0.43) | MALT1NOTUMHTR2BHTR2CKDM4E | |
| SCHEMBL9824427 | 0.72 | CA1 (0.40) | KDM4ESMN1; SMN2HSD17B3 | |
| SCHEMBL9209686 | 0.71 | FABP7 (0.36) | NOTUMFABP7FABP5 | |
| SCHEMBL9209494 | 0.70 | MALT1 (0.38) | MALT1NOTUMHTR2BHTR2C | |
| SCHEMBL10656312 | 0.70 | KMT2A (0.31) | KMT2A | |
| SCHEMBL1081511 | 0.67 | FABP7 (0.56) | KMT2ASMN1; SMN2FABP7FABP5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389425-B1 | Benzotiopyranyl amines | CIBA GEIGY AG (CH) | 1995-04-26 | — | — | EP | disclosed |
| EP-0389425-A1 | Benzotiopyranyl amines | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |