SCHEMBL10656312

SCHEMBL10656312

O=C(O)OC1CSc2ccsc2C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.31
DAO P14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10652126 0.77 KMT2A (0.33) KMT2ADAO
SCHEMBL9219428 0.74 FABP7 (0.39) KMT2A
SCHEMBL9218695 0.70 PTPN1 (0.40) KMT2A
SCHEMBL9220559 0.70 MALT1 (0.43) KMT2A
SCHEMBL10514435 0.70
SCHEMBL9824427 0.68 CA1 (0.40)
SCHEMBL9213539 0.68 RYR2 (0.47)
SCHEMBL9825214 0.68 ACHE (0.38)
SCHEMBL9209686 0.64 FABP7 (0.36)
SCHEMBL750015 0.63 NPC1 (0.43) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0280268-A1 Thienothiopyrans CIBA-GEIGY AG (CH) 1988-08-31 EP disclosed