SCHEMBL9220569

SCHEMBL9220569

Brc1csc(Br)c1Br.O=C(O)Cl

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
GSK3B P49841 4/20 0.45
GPR35 Q9HC97 7/20 0.38
DAO P14920 1/20 0.35
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1629367 0.82
SCHEMBL27447830 0.71 GSK3B (0.61) TSHRGSK3BGPR35DAOCES2
SCHEMBL4584288 0.71 TSHR (1.00) TSHRGSK3BGPR35DAOCES2
SCHEMBL4584130 0.68 GSK3B (0.59) TSHRGSK3BGPR35DAO
SCHEMBL623033 0.68 TSHR (0.52) TSHRGSK3BGPR35DAOCES2
SCHEMBL7041123 0.65 GSK3B (0.55) TSHRGSK3BGPR35DAOCES2
SCHEMBL4811503 0.64 TSHR (0.42) TSHRGSK3BGPR35
SCHEMBL2982713 0.62 GSK3B (0.57) TSHRGSK3BGPR35CES2CES1
SCHEMBL16414224 0.62 TSHR (0.40) TSHRGSK3BGPR35CES2CES1
Krypton SCHEMBL29291458 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450355-B1 Compounds for the combat against plant diseases DEGUSSA (DE) 1995-08-09 EP disclosed
EP-0450355-A1 Compounds for the combat against plant diseases Degussa Aktiengesellschaft (DE) 1991-10-09 EP disclosed