Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.35 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.35 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220609 | 0.83 | MGAM (0.61) | MGAMKDM4EALOX15TSHRACMSD | |
| SCHEMBL12405037 | 0.77 | MGAM (0.63) | MGAMKDM4EALOX15TSHRACMSD | |
| SCHEMBL12501532 | 0.73 | MGAM (0.69) | MGAMKDM4EALOX15TSHRACMSD | |
| SCHEMBL14806709 | 0.71 | KMT2A (0.60) | MGAMKDM4EALOX15TSHRACMSD | |
| SCHEMBL9319235 | 0.71 | MGAM (0.55) | MGAMKDM4EALOX15TSHRACMSD | |
| SCHEMBL23722355 | 0.69 | MGAM (0.58) | MGAMKDM4EALOX15TSHRACMSD | |
| SCHEMBL2715968 | 0.69 | MGAM (0.53) | MGAMKDM4EALOX15TSHRACMSD | |
| SCHEMBL20772073 | 0.69 | MGAM (0.53) | MGAMKDM4EALOX15TSHRACMSD | |
| SCHEMBL950437 | 0.67 | MGAM (0.60) | MGAMKDM4EALOX15TSHRACMSD | |
| SCHEMBL28278979 | 0.67 | MGAM (0.60) | MGAMKDM4EALOX15TSHRACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126617-A | PROPHYLAXIS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4064248-A | TREATMENT OF ASTHMA | THE UPJOHN COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-3959289-A | PROPHYLACTICS IN ALLERGIES | THE UPJOHN COMPANY (US) | 1976-05-25 | — | — | US | disclosed |