Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | BRD2 | P25440 | 1/20 | 0.63 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.59 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.59 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | INMT | O95050 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20602673 | 0.96 | CRBN (0.59) | BRD4BRD2CRBNFKBP5OR51E2 | |
| SCHEMBL28086029 | 0.95 | CRBN (0.57) | BRD4BRD2CRBNFKBP5OR51E2 | |
| SCHEMBL5899535 | 0.95 | CRBN (0.57) | BRD4BRD2CRBNFKBP5OR51E2 | |
| Methylpyrrolidone SCHEMBL69069 | 0.94 | BRD4 (0.65) | BRD4BRD2CRBNFKBP5OR51E2 | |
| Methylpyrrolidone SCHEMBL10583981 | 0.93 | BRD4 (0.63) | BRD4BRD2CRBNFKBP5OR51E2 | |
| 2-Pyrrolidone SCHEMBL7931523 | 0.91 | BRD4 (0.55) | BRD4BRD2CRBNFKBP5OR51E2 | |
| Methylpyrrolidone SCHEMBL28178483 | 0.86 | BRD4 (0.55) | BRD4BRD2CRBNFKBP5OR51E2 | |
| Methylpyrrolidone SCHEMBL28246488 | 0.86 | BRD4 (0.55) | BRD4BRD2CRBNFKBP5OR51E2 | |
| Methylpyrrolidone SCHEMBL28659452 | 0.80 | BRD4 (0.90) | BRD4BRD2GAAINMTMEN1 | |
| Methylpyrrolidone SCHEMBL28665050 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348641-B1 | Process for the preparation of tetrahydrofolates | EPROVA AG (CH) | 1995-06-21 | — | — | EP | disclosed |