Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.57 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | BRD2 | P25440 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28086029 | 1.00 | CRBN (0.57) | CRBNFKBP5BRD4BRD2KDM4E | |
| SCHEMBL20602673 | 0.98 | CRBN (0.59) | CRBNFKBP5BRD4BRD2KDM4E | |
| 2-Pyrrolidone SCHEMBL7931523 | 0.96 | BRD4 (0.55) | CRBNFKBP5BRD4BRD2KDM4E | |
| Methylpyrrolidone SCHEMBL9220632 | 0.95 | BRD4 (0.63) | CRBNFKBP5BRD4BRD2KDM4E | |
| Methylpyrrolidone SCHEMBL69069 | 0.89 | BRD4 (0.65) | CRBNFKBP5BRD4BRD2KDM4E | |
| Methylpyrrolidone SCHEMBL10583981 | 0.87 | BRD4 (0.63) | CRBNFKBP5BRD4BRD2KDM4E | |
| SCHEMBL7359128 | 0.83 | BRD4 (0.61) | CRBNFKBP5BRD4BRD2KDM4E | |
| SCHEMBL7359122 | 0.83 | CRBN (0.64) | CRBNFKBP5BRD4BRD2KDM4E | |
| SCHEMBL6886758 | 0.82 | BRD4 (0.80) | BRD4BRD2GAAACHEALDH1A1 | |
| SCHEMBL54926 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138475-B2 | Compositions for golf equipment | ACUSHNET COMPANY (US) | 2006-11-21 | — | — | US | disclosed |
| US-20040220377-A1 | Compositions for golf equipment | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2004-11-04 | — | — | US | disclosed |