Methylpyrrolidone

Methylpyrrolidone

SCHEMBL69069

CN1CCCC1=O.O=C1CCCN1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.65
BRD2 P25440 1/20 0.65
OR51E2 Q9H255 1/20 0.58
CRBN Q96SW2 2/20 0.50
FKBP5 Q13451 1/20 0.50
GAA P10253 5/20 0.44
KDM4E B2RXH2 3/20 0.44
POLB P06746 1/20 0.44
INMT O95050 2/20 0.34
ALOX5 P09917 2/20 0.34
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
MAPT P10636 3/20 0.33
ALDH1A1 P00352 3/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
IDE P14735 1/20 0.33
PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpyrrolidone SCHEMBL10583981 0.98 BRD4 (0.63) BRD4BRD2OR51E2CRBNFKBP5
Methylpyrrolidone SCHEMBL9220632 0.94 BRD4 (0.63) BRD4BRD2OR51E2CRBNFKBP5
2-Pyrrolidone SCHEMBL7931523 0.93 BRD4 (0.55) BRD4BRD2OR51E2CRBNFKBP5
Methylpyrrolidone SCHEMBL28246488 0.92 BRD4 (0.55) BRD4BRD2OR51E2CRBNFKBP5
Methylpyrrolidone SCHEMBL28178483 0.92 BRD4 (0.55) BRD4BRD2OR51E2CRBNFKBP5
SCHEMBL20602673 0.91 CRBN (0.59) BRD4BRD2OR51E2CRBNFKBP5
SCHEMBL5899535 0.89 CRBN (0.57) BRD4BRD2OR51E2CRBNFKBP5
SCHEMBL28086029 0.89 CRBN (0.57) BRD4BRD2OR51E2CRBNFKBP5
Methylpyrrolidone SCHEMBL28178484 0.86 BRD4 (0.49) BRD4BRD2OR51E2CRBNFKBP5
Methylpyrrolidone SCHEMBL28659452 0.81 BRD4 (0.90) BRD4BRD2GAAINMTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002543223-A 2002-12-17 JP claimed
EP-1177218-A1 METHOD OF IMMEDIATELY TERMINATING FREE-RADICAL POLYMERISATION PROCESSES BASF AKTIENGESELLSCHAFT (DE) 2002-02-06 EP claimed
WO-2000064947-A1 METHOD OF IMMEDIATELY TERMINATING FREE-RADICAL POLYMERISATION PROCESSES BASF AKTIENGESELLSCHAFT (DE) 2000-11-02 WO claimed
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP claimed
US-20240065963-A1 MULTICOMPONENT COMPOSITION (Michael Addition) WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2024-02-29 US disclosed
US-11766394-B2 Multicomponent composition (Michael addition) WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2023-09-26 US disclosed
WO-2023132640-A1 CURRENT COLLECTOR FOR SECONDARY BATTERY AND METHOD FOR MANUFACTURING SAME 주식회사 릴엠 2023-07-13 WO disclosed
WO-2023132641-A1 CURRENT COLLECTOR FOR SECONDARY BATTERY AND MANUFACTURING METHOD THEREFOR 주식회사 릴엠 2023-07-13 WO disclosed
WO-2023075520-A1 CYLINDRICAL SECONDARY BATTERY COMPRISING IMPROVED CURRENT COLLECTOR PLATE, AND BATTERY PACK AND VEHICLE INCLUDING SAME 주식회사 엘지에너지솔루션 2023-05-04 WO disclosed
CN-112038708-B Lithium ion battery roll core structure and manufacturing method thereof 合肥国轩高科动力能源有限公司 2022-06-10 CN disclosed
US-20220117877-A1 MULTICOMPONENT COMPOSITION (Michael Addition) HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2022-04-21 US disclosed
EP-0666729-A1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1995-08-16 EP disclosed
EP-0647690-A2 Pigment dispersion composition, display apparatus, and method of manufacturing the apparatus KABUSHIKI KAISHA TOSHIBA (JP) 1995-04-12 EP disclosed
WO-1994023694-A1 COSMETIC COMPOSITION CONTAINING CERAMIDE PRECURSORS UNILEVER PLC (GB) 1994-10-27 WO disclosed
WO-1994009750-A1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1994-05-11 WO disclosed
EP-0543948-A1 A MICROWAVE ACTIVE COATING MATERIAL INCLUDING A POLYMERIC RESIN THE PROCTER & GAMBLE COMPANY (US) 1993-06-02 EP disclosed
WO-1992003509-A1 A MICROWAVE ACTIVE COATING MATERIAL INCLUDING A POLYMERIC RESIN THE PROCTER & GAMBLE COMPANY (US) 1992-03-05 WO disclosed
US-5066413-A Fabric softening, antistatic agents, avoiding residues CREATIVE PRODUCTS RESOURCE ASSOCIATES, LTD. (US) 1991-11-19 US disclosed
US-5034222-A Solid having gelled phase and granular foam phases; substained release CREATIVE PRODUCTS RESOURCE ASSOCIATES, LTD. (US) 1991-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220117877-A1 MULTICOMPONENT COMPOSITION (Michael Addition) KRT18, EXOSC10, CUTA BRD4 1485/4885BRD2 2359/4885OR51E2 2307/4885
US-11766394-B2 Multicomponent composition (Michael addition) KRT18, EXOSC10, CUTA BRD4 1485/4885BRD2 2359/4885OR51E2 2307/4885
US-20240065963-A1 MULTICOMPONENT COMPOSITION (Michael Addition) KRT18, EXOSC10, CUTA BRD4 1485/4885BRD2 2359/4885OR51E2 2307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.