Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011246 | 0.85 | MAPK1 (0.44) | MAPK1KDM4EKMT2AMEN1NPC1 | |
| SCHEMBL1070071 | 0.83 | GPR132 (0.51) | MAPK1USP30 | |
| SCHEMBL9222653 | 0.82 | LCK (0.54) | MAPK1KDM4ETHRBKMT2AMEN1 | |
| SCHEMBL9011252 | 0.79 | MAPK1 (0.71) | MAPK1THRBKMT2AMEN1NPC1 | |
| SCHEMBL6371255 | 0.75 | HDAC1 (0.46) | KMT2AMEN1CYP3A4ALDH1A1NPSR1 | |
| SCHEMBL6371247 | 0.75 | HDAC1 (0.46) | KMT2AMEN1CYP3A4ALDH1A1NPSR1 | |
| SCHEMBL6371258 | 0.75 | HDAC1 (0.46) | KMT2AMEN1CYP3A4ALDH1A1NPSR1 | |
| SCHEMBL1070049 | 0.73 | GPR132 (0.52) | MAPK1 | |
| SCHEMBL1071435 | 0.72 | GPR132 (0.54) | MAPK1 | |
| SCHEMBL11859682 | 0.72 | PTPN1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389623-A | Redox carriers for brain-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1995-02-14 | — | — | US | disclosed |
| US-5087618-A | Antiviral, anticancer, antitumor agents | UNIVERSITY OF FLORIDA (US) | 1992-02-11 | — | — | US | disclosed |
| US-4829070-A | PRODRUG FOR SUSTAINED RELEASE OF DOPAMINE | UNIVERSITY OF FLORIDA (US) | 1989-05-09 | — | — | US | disclosed |