Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.40 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070071 | 0.90 | GPR132 (0.51) | MAPK1USP30GPR132CTSVCTSL | |
| SCHEMBL9220680 | 0.85 | MAPK1 (0.48) | MAPK1ALDH1A1USP30KMT2AKDM4E | |
| SCHEMBL9011337 | 0.81 | ALDH1A1 (0.48) | MAPK1SMN1; SMN2ALDH1A1MAPTGPR132 | |
| SCHEMBL8722708 | 0.80 | GRIA1 (0.56) | SMN1; SMN2ALDH1A1MAPTGPR132KMT2A | |
| SCHEMBL8722398 | 0.80 | GRIA1 (0.56) | SMN1; SMN2ALDH1A1MAPTGPR132KMT2A | |
| SCHEMBL1070049 | 0.79 | GPR132 (0.52) | MAPK1GPR132CTSVCTSLCTSB | |
| SCHEMBL1071435 | 0.78 | GPR132 (0.54) | MAPK1GPR132CMKLR2CMKLR1 | |
| SCHEMBL11859682 | 0.78 | PTPN1 (0.52) | GPR132CTSL | |
| SCHEMBL9011252 | 0.77 | MAPK1 (0.71) | MAPK1SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL29809632 | 0.74 | ECE1 (0.54) | MAPK1SMN1; SMN2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525727-A | ANALGESIC OR NARCOTIC ANTAGONIST | UNIVERSITY OF FLORIDA (US) | 1996-06-11 | — | — | US | disclosed |
| US-5187158-A | Sustained delivery of viricides | UNIVERSITY OF FLORIDA (US) | 1993-02-16 | — | — | US | disclosed |
| US-5008257-A | Penicillin or cephalosporin antibiotics | UNIVERSITY OF FLORIDA (US) | 1991-04-16 | — | — | US | disclosed |
| US-4900837-A | Brain-specific drug delivery of steroid sex hormones cleaved from pyridinium carboxylates and dihydro-pyridine carboxylate precursors | UNIVERSITY OF FLORIDA (US) | 1990-02-13 | — | — | US | disclosed |
| US-4880921-A | Brain-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1989-11-14 | — | — | US | disclosed |
| US-4824850-A | DIHYDROPYRIDINE-PYRIDINIUM SALT REDOX CARRIER | UNIVERSITY OF FLORIDA (US) | 1989-04-25 | — | — | US | disclosed |