Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223518 | 0.90 | CYP3A4 (0.59) | THRATHRBTDP1CYP4F2CYP4A11 | |
| SCHEMBL9227625 | 0.85 | ALOX5 (0.41) | THRATHRBTDP1CYP4F2CYP4A11 | |
| SCHEMBL889921 | 0.84 | CYP4F2 (0.57) | TDP1CYP4F2CYP4A11ALOX5ALDH1A1 | |
| SCHEMBL15080678 | 0.82 | CYP4F2 (0.46) | TDP1CYP4F2CYP4A11ALOX5ALDH1A1 | |
| SCHEMBL6071507 | 0.82 | ALOX5 (0.52) | TDP1CYP4F2CYP4A11ALOX5ALDH1A1 | |
| SCHEMBL9228405 | 0.82 | ALOX5 (0.39) | THRATHRBTDP1CYP4F2CYP4A11 | |
| SCHEMBL9225923 | 0.82 | CYP4F2 (0.39) | CYP4F2CYP4A11ALOX5ALDH1A1CYP4Z1 | |
| SCHEMBL12386503 | 0.81 | ALOX5 (0.49) | TDP1CYP4F2CYP4A11ALOX5ALDH1A1 | |
| SCHEMBL26049317 | 0.81 | GAA (0.47) | ALOX5ALDH1A1 | |
| SCHEMBL9226392 | 0.80 | ALOX5 (0.48) | TDP1CYP4F2CYP4A11ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636647-A1 | Use of substituted phenols as fatique protectors for dynamically stressed elastomers | BAYER AG (DE) | 1995-02-01 | — | — | EP | disclosed |