SCHEMBL9225923

SCHEMBL9225923

CCCC(C)COC(=O)CCc1cc(C)c(O)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
PTPN1 P18031 1/20 0.38
ESR1 P03372 2/20 0.38
ALOX5 P09917 2/20 0.37
ALDH1A1 P00352 1/20 0.36
CYP4Z1 Q86W10 1/20 0.35
CNR2 P34972 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
APP P05067 1/20 0.35
MAPT P10636 1/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
LTA4H P09960 1/20 0.34
S1PR1 P21453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9229651 0.85 ALOX5 (0.38) CYP4F2CYP4A11ESR1ALOX5ALDH1A1
SCHEMBL9227625 0.84 ALOX5 (0.41) CYP4F2CYP4A11ALOX5ALDH1A1CYP4Z1
SCHEMBL14438472 0.82 GAA (0.43) PTPN1ESR1CNR2MAPTLTA4H
SCHEMBL9225613 0.82 CYP4F2 (0.36) CYP4F2CYP4A11ESR1ALOX5ALDH1A1
SCHEMBL9228405 0.82 ALOX5 (0.39) CYP4F2CYP4A11ESR1ALOX5ALDH1A1
SCHEMBL9220767 0.82 THRA (0.44) CYP4F2CYP4A11ESR1ALOX5ALDH1A1
SCHEMBL9226396 0.81 ALOX5 (0.42) CYP4F2CYP4A11ESR1ALOX5ALDH1A1
SCHEMBL889921 0.81 CYP4F2 (0.57) CYP4F2CYP4A11ESR1ALOX5ALDH1A1
SCHEMBL19024850 0.81 CYP4F2 (0.51) CYP4F2CYP4A11ALDH1A1CYP4Z1MAPT
SCHEMBL9223518 0.81 CYP3A4 (0.59) CYP4F2CYP4A11ESR1ALDH1A1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0636647-A1 Use of substituted phenols as fatique protectors for dynamically stressed elastomers BAYER AG (DE) 1995-02-01 EP disclosed