SCHEMBL9220799

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12157085	0.88	HTT (0.53)	POLBHTTNPSR1L3MBTL1AGTR1
	SCHEMBL14576458	0.85	POLB (0.49)	POLBHTTNPSR1L3MBTL1AGTR1
	SCHEMBL28570761	0.83	POLB (0.50)	POLBHTTNPSR1L3MBTL1AGTR1
	SCHEMBL28570763	0.83	POLB (0.50)	POLBHTTNPSR1L3MBTL1AGTR1
	SCHEMBL19003505	0.81	POLB (0.47)	POLBHTTNPSR1L3MBTL1CA1
	SCHEMBL9220794	0.81	POLB (0.51)	POLBHTTNPSR1L3MBTL1CA1
	SCHEMBL29110960	0.80	POLB (0.59)	POLBHTTNPSR1L3MBTL1LMNA
	SCHEMBL14576778	0.79	POLB (0.62)	POLBHTTNPSR1L3MBTL1LMNA
	SCHEMBL8531258	0.79	ADRA1A (0.57)	HTTLMNACYP1A2CA1CA2
	SCHEMBL17755320	0.79	POLB (0.62)	POLBHTTNPSR1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.