Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 19/20 | 0.66 |
| ▸ | IDO1 | P14902 | 18/20 | 0.66 |
| ▸ | IDO2 | Q6ZQW0 | 10/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222336 | 0.88 | TDO2 (0.63) | TDO2IDO1IDO2MEN1APAF1 | |
| SCHEMBL26857739 | 0.82 | IDO1 (0.69) | TDO2IDO1IDO2MEN1APAF1 | |
| Hydrochloric Acid SCHEMBL26614206 | 0.81 | TDO2 (0.68) | TDO2IDO1IDO2MEN1APAF1 | |
| SCHEMBL26857020 | 0.81 | IDO1 (0.59) | TDO2IDO1IDO2MEN1APAF1 | |
| SCHEMBL9115282 | 0.80 | IDO1 (0.55) | TDO2IDO1IDO2MEN1APAF1 | |
| SCHEMBL9105370 | 0.80 | IDO1 (1.00) | TDO2IDO1IDO2MEN1APAF1 | |
| SCHEMBL26614183 | 0.79 | TDO2 (0.71) | TDO2IDO1IDO2MEN1APAF1 | |
| SCHEMBL9103054 | 0.78 | TDO2 (0.85) | TDO2IDO1IDO2MEN1APAF1 | |
| SCHEMBL26614113 | 0.77 | TDO2 (0.79) | TDO2IDO1IDO2MEN1APAF1 | |
| SCHEMBL30639087 | 0.77 | TDO2 (0.64) | TDO2IDO1IDO2MEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441955-A | Tuberculosis | PATHOGENESIS CORPORATION (US) | 1995-08-15 | — | — | US | disclosed |
| WO-1995013807-A1 | INDOLO[2,1-b]QUINAZOLINE-6,12-DIONE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |