Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13159061 | 0.84 | CYP46A1 (0.44) | KDM4ENR4A2CA1CA2GAA | |
| SCHEMBL20803216 | 0.82 | ALDH1A1 (0.36) | KDM4ECA1CA2GLAGAA | |
| SCHEMBL9857862 | 0.82 | KDM4E (0.40) | KDM4ECYP1A2CYP2C19CYP2D6HSD17B10 | |
| SCHEMBL2467212 | 0.82 | NR4A2 (0.43) | KDM4ENR4A2GAAHSD17B10ALDH1A1 | |
| SCHEMBL13159056 | 0.82 | ABL1 (0.49) | KDM4ENR4A2PLA2G2AALDH1A1MAPT | |
| SCHEMBL31363552 | 0.82 | ALDH1A1 (0.36) | KDM4ECA1CA2GLAGAA | |
| SCHEMBL11165984 | 0.81 | ALDH1A1 (0.43) | KDM4ECA1CA2GAAHSD17B10 | |
| SCHEMBL2470933 | 0.81 | EGFR (0.48) | KDM4ECYP2D6ALDH1A1MAPTPKM | |
| SCHEMBL3483627 | 0.79 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTHTTKMT2A | |
| SCHEMBL3484162 | 0.79 | CPS1 (0.43) | GAAALDH1A1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565721-B1 | 1,4-BENZOTHIAZEPINE DERIVATIVE | KANEKO NOBORU (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5416066-A | FOR THE PREVENTION OF MYOCARDIAL INFARCTION OR INHIBITING MYOCARDIAL NECROSIS | KIRIN BREWERY CO., LTD. (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0565721-A1 | 1,4-BENZOTHIAZEPINE DERIVATIVE | KANEKO, Noboru (JP) | 1993-10-20 | — | — | EP | disclosed |