Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 13/20 | 0.61 |
| ▸ | PPARG | P37231 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | DHPS | P49366 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9223842 | 0.99 | NR1H4 (0.60) | NR1H4PPARGNPC1RAB9APPARA | |
| SCHEMBL9220304 | 0.94 | NR1H4 (0.64) | NR1H4PPARGNPC1RAB9APPARA | |
| Hydrochloric Acid SCHEMBL9227079 | 0.92 | NR1H4 (0.62) | NR1H4PPARGRAB9APPARAESRRG | |
| SCHEMBL9221688 | 0.90 | NR1H4 (0.49) | NR1H4PPARGPPARAPPARD | |
| SCHEMBL9229693 | 0.90 | RXFP1 (0.50) | NR1H4PPARGPPARAPPARD | |
| SCHEMBL9228612 | 0.89 | KMT2A (0.55) | NR1H4PPARGNPC1RAB9APPARA | |
| Hydrochloric Acid SCHEMBL9223697 | 0.88 | NR1H4 (0.56) | NR1H4PPARGNPC1RAB9APPARA | |
| SCHEMBL9223763 | 0.87 | PPARG (0.60) | NR1H4PPARGNPC1RAB9APPARA | |
| SCHEMBL9224692 | 0.87 | MAPT (0.47) | NR1H4PPARGNPC1RAB9APPARA | |
| Oxalic Acid SCHEMBL9228701 | 0.87 | NR1H4 (0.47) | NR1H4PPARGNPC1RAB9APPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | claimed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | claimed |
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |