Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.60 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228612 | 0.89 | KMT2A (0.55) | PPARGPPARANAMPTMAPTNR1H4 | |
| Oxalic Acid SCHEMBL9228701 | 0.89 | NR1H4 (0.47) | PPARGPPARANAMPTMAPTNR1H4 | |
| Hydrochloric Acid SCHEMBL9229366 | 0.88 | NAMPT (0.55) | PPARGNAMPTMAPTNPC1RAB9A | |
| SCHEMBL9229693 | 0.87 | RXFP1 (0.50) | PPARGPPARANAMPTMAPTNR1H4 | |
| SCHEMBL9221455 | 0.87 | NR1H4 (0.61) | PPARGPPARANR1H4PPARDNPC1 | |
| SCHEMBL9224692 | 0.86 | MAPT (0.47) | PPARGPPARANAMPTMAPTNR1H4 | |
| Hydrochloric Acid SCHEMBL9223842 | 0.86 | NR1H4 (0.60) | PPARGPPARANR1H4PPARDNPC1 | |
| Hydrochloric Acid SCHEMBL9221799 | 0.85 | MAPT (0.47) | PPARGPPARANAMPTMAPTNR1H4 | |
| Hydrochloric Acid SCHEMBL9220360 | 0.84 | MAPT (0.42) | PPARGNAMPTMAPTBACE1ALDH1A1 | |
| SCHEMBL9220304 | 0.81 | NR1H4 (0.64) | PPARGPPARANR1H4PPARDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |