Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 8/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69761 | 0.89 | SCD (0.42) | P2RY12CACNA1BSCDKMT2AKIT | |
| SCHEMBL92228 | 0.87 | P2RY12 (0.41) | P2RY12EPHX2SCDKMT2A | |
| SCHEMBL70788 | 0.86 | KMT2A (0.40) | CYP2D6P2RY12EPHX2SCDKMT2A | |
| SCHEMBL29384497 | 0.86 | KMT2A (0.40) | CYP2D6P2RY12EPHX2SCDKMT2A | |
| SCHEMBL70832 | 0.86 | SCD (0.43) | P2RY12EPHX2SCDKMT2AKIT | |
| SCHEMBL68601 | 0.85 | KMT2A (0.40) | P2RY12EPHX2SCDKMT2A | |
| SCHEMBL29385018 | 0.85 | KMT2A (0.40) | P2RY12EPHX2SCDKMT2A | |
| SCHEMBL69476 | 0.82 | KMT2A (0.41) | P2RY12EPHX2SCDKMT2A | |
| SCHEMBL29384702 | 0.82 | KMT2A (0.41) | P2RY12EPHX2SCDKMT2A | |
| SCHEMBL69930 | 0.80 | SCD (0.43) | P2RY12EPHX2SCDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129376-B2 | Piperidine derivatives as inhibitors of stearoyl-CoA desaturase | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-03-06 | — | — | US | disclosed |
| WO-2009117676-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-24 | — | — | WO | disclosed |
| US-20090239810-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239810-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | SCD, SCD5, FADS2 | CYP2D6 2464/4885P2RY12 3918/4885CACNA1B 2592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.