SCHEMBL9221963

SCHEMBL9221963

COc1cc(OC)nc(Oc2cccc(Oc3ccccc3)c2C(=O)OCc2ccccc2)n1

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.52
CYP2C9 P11712 3/20 0.52
CYP2C19 P33261 3/20 0.52
CYP3A4 P08684 2/20 0.52
GAA P10253 1/20 0.52
ALDH1A1 P00352 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NPSR1 Q6W5P4 2/20 0.47
ATM Q13315 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9193808 0.95 ALDH1A1 (0.52) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9765529 0.94 CYP1A2 (0.47) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL10534108 0.93 CYP1A2 (0.59) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9191891 0.89 ALDH1A1 (0.48) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9622229 0.88 NPSR1 (0.56) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9615079 0.87 ALDH1A1 (0.52) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9380916 0.85 ALDH1A1 (0.45) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL8580525 0.84 ALDH1A1 (0.49) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9412143 0.83 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL9754362 0.83 ALDH1A1 (0.48) CYP1A2CYP2C9CYP2C19CYP3A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0287072-B1 2-Phenoxypyrimidine derivatives and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO (JP) 1995-07-05 EP disclosed
US-5019151-A 2-phenoxyprimidine derivative and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-05-28 US disclosed
US-4946495-A 2-phenoxypyrimidine derivative and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-08-07 US disclosed
EP-0287072-A2 2-Phenoxypyrimidine derivatives and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-10-19 EP disclosed