SCHEMBL9380916

SCHEMBL9380916

COc1cc(OC)nc(Oc2cccc(C(F)(F)F)c2C(=O)OCc2ccccc2)n1

nearest known ligand 0.71

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
GAA P10253 1/20 0.44
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9193808 0.89 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C9
SCHEMBL9191891 0.85 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C9
SCHEMBL9221963 0.85 CYP1A2 (0.52) ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C9
SCHEMBL9622229 0.84 NPSR1 (0.56) ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C9
SCHEMBL9221271 0.84 CYP1A2 (0.46) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL9615079 0.83 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C9
SCHEMBL9765529 0.83 CYP1A2 (0.47) ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C9
SCHEMBL9317266 0.81 CYP1A2 (0.44) ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C9
SCHEMBL8580525 0.81 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C9
SCHEMBL10534108 0.81 CYP1A2 (0.59) ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0287079-B1 2-Phenoxypyrimidine derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO (JP) 1994-10-12 EP disclosed
US-4889552-A 2-Phenoxypyrimidine derivative and herbidical composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-12-26 US disclosed
EP-0287079-A2 2-Phenoxypyrimidine derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-10-19 EP disclosed