SCHEMBL9221981

SCHEMBL9221981

CC(C)CCCCCCCOC(=O)CCc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.37
GAA P10253 4/20 0.36
KMT2A Q03164 4/20 0.35
MAOB P27338 3/20 0.35
MEN1 O00255 2/20 0.35
MAOA P21397 2/20 0.35
TDP1 Q9NUW8 1/20 0.34
ACHE P22303 1/20 0.34
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
LMNA P02545 1/20 0.33
AGTR1 P30556 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PDE1A P54750 1/20 0.33
PDE1B Q01064 1/20 0.33
PDE1C Q14123 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141324 1.00 ALOX5 (0.37) ALOX5GAAKMT2AMAOBMEN1
SCHEMBL672759 0.94 ALOX5 (0.41) ALOX5GAAKMT2AMAOBMEN1
SCHEMBL31361790 0.94 ALOX5 (0.41) ALOX5GAAKMT2AMAOBMEN1
SCHEMBL104649 0.93 ALOX5 (0.42) ALOX5GAAKMT2AMAOBMEN1
SCHEMBL769282 0.91 EPHX2 (0.32) ALOX5GAAKMT2AMAOBMEN1
SCHEMBL7144050 0.90 PDE1A (0.31) ALOX5GAAKMT2AMAOBMEN1
SCHEMBL23533531 0.90 CNR2 (0.41) ALOX5GAAKMT2AMAOBMEN1
SCHEMBL9871733 0.90 CNR2 (0.41) ALOX5GAAKMT2AMAOBMEN1
SCHEMBL2491248 0.90 CNR2 (0.41) ALOX5GAAKMT2AMAOBMEN1
SCHEMBL5630244 0.90 CNR2 (0.41) ALOX5GAAKMT2AMAOBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5476882-A Containing 2,2,6,6-tetraalkylpiperidine derivative CIBA-GEIGY CORPORATION (US) 1995-12-19 US disclosed
EP-0296391-B1 LIGHT-STABILIZED POLYMER MICROPARTICLES CONTAINING EPOXY GROUPS CIBA-GEIGY AG (CH) 1993-07-07 EP disclosed
EP-0226538-B1 LIGHT STABILIZED POLYMER MICROPARTICLES Ciba SC Holding AG (CH) 1991-09-11 EP disclosed
US-5032498-A Soluble stabilizers CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4973702-A AMIDES AND ESTERS, UV STABILIZERS FOR PLASTICS AND PHOTOGRAPHIC MATERIALS CIBA-GEIGY CORPORATION (US) 1990-11-27 US disclosed
US-4894399-A Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY CORPORATION (US) 1990-01-16 US disclosed
US-4853471-A 2-(2-Hydroxyphenyl)-benztriazoles, their use as UV-absorbers and their preparation CIBA-GEIGY CORPORATION (US) 1989-08-01 US disclosed
EP-0226538-A2 Light stabilized polymer microparticles CIBA-GEIGY AG (CH) 1987-06-24 EP disclosed
EP-0057160-B1 2-(2-HYDROXYPHENYL)-BENZOTRIAZOLES, THEIR USE AS ULTRAVIOLET STABILIZERS AND THEIR PREPARATION CIBA-GEIGY AG (CH) 1985-06-19 EP disclosed
EP-0057160-A1 2-(2-Hydroxyphenyl)-benzotriazoles, their use as ultraviolet stabilizers and their preparation CIBA-GEIGY AG (CH) 1982-08-04 EP disclosed