Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141324 | 0.90 | ALOX5 (0.37) | PDE1APDE1BPDE1CALOX5GAA | |
| SCHEMBL9221981 | 0.90 | ALOX5 (0.37) | PDE1APDE1BPDE1CALOX5GAA | |
| SCHEMBL2641197 | 0.87 | MC4R (0.32) | GAAMEN1KMT2A | |
| SCHEMBL5693435 | 0.84 | GAA (0.40) | GAAMEN1KMT2AMAOAMAOB | |
| SCHEMBL672759 | 0.84 | ALOX5 (0.41) | ALOX5GAAMEN1KMT2AMAOA | |
| SCHEMBL769282 | 0.83 | EPHX2 (0.32) | ALOX5GAAMEN1KMT2AMAOA | |
| SCHEMBL104649 | 0.83 | ALOX5 (0.42) | ALOX5GAAMEN1KMT2AMAOA | |
| SCHEMBL207238 | 0.82 | EPHX2 (0.39) | GAAKMT2AMAOAMAOBP2RY10 | |
| SCHEMBL23533531 | 0.81 | CNR2 (0.41) | ALOX5GAAMEN1KMT2AMAOA | |
| SCHEMBL9871733 | 0.81 | CNR2 (0.41) | ALOX5GAAMEN1KMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515051-B2 | Stability and durability and a low loss rate when incorporated into automotive coatings; soluble in a variety of substrates including thermoplastic polymers and often are colorless | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-04 | — | — | US | disclosed |
| US-6458872-B1 | FOR USE IN AUTOMOTIVE COATINGS, THERMOPLASTIC FORMULATIONS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-10-01 | — | — | US | disclosed |
| US-20020099221-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2002-07-25 | — | — | US | disclosed |
| US-20020065341-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2002-05-30 | — | — | US | disclosed |
| US-6262151-B1 | FOR AUTOMOTIVE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-17 | — | — | US | disclosed |
| US-6166218-A | Benzotriazole UV absorbers having enhanced durability | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099221-A1 | Benzotriazole UV absorbers having enhanced durability | TERT, AHR, ARNT | PDE1A 4869/4885PDE1B 4865/4885PDE1C 4876/4885 |
| US-20020065341-A1 | Benzotriazole UV absorbers having enhanced durability | TERT, AHR, ARNT | PDE1A 4869/4885PDE1B 4865/4885PDE1C 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.