Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.55 |
| ▸ | HLCS | P50747 | 6/20 | 0.51 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309033 | 0.85 | TDP1 (0.57) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL19901346 | 0.85 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21524656 | 0.85 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL12724896 | 0.85 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31332171 | 0.84 | CAPN1 (0.62) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378106 | 0.84 | CAPN1 (0.59) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL8146132 | 0.83 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378129 | 0.82 | TDP1 (0.66) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL6270371 | 0.81 | TDP1 (0.60) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL19960776 | 0.81 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5426029-A | Measuring soluble clusters of differentiation 35 in a sample by contacting with anti-cd35 polyclonal antibodies which allow immunospecific binding to occur, detecting and measuring binding which occurs | T CELL DIAGNOSTICS, INC. (US) | 1995-06-20 | — | — | US | disclosed |
| US-5292636-A | Immunospecific binding | T CELL DIAGNOSTICS, INC. (US) | 1994-03-08 | — | — | US | disclosed |
| WO-1990004180-A1 | THERAPEUTIC AND DIAGNOSTIC METHODS USING SOLUBLE T CELL SURFACE MOLECULES | T CELL SCIENCES, INC. (US) | 1990-04-19 | — | — | WO | disclosed |