Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | IDE | P14735 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HLCS | P50747 | 5/20 | 0.60 |
| ▸ | CA12 | O43570 | 5/20 | 0.57 |
| ▸ | CA1 | P00915 | 5/20 | 0.57 |
| ▸ | CA2 | P00918 | 5/20 | 0.57 |
| ▸ | CA9 | Q16790 | 5/20 | 0.57 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19901346 | 1.00 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21524656 | 1.00 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL27414509 | 0.93 | TDP1 (0.66) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21958835 | 0.92 | TDP1 (0.70) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL8146132 | 0.91 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378129 | 0.90 | TDP1 (0.66) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL319055 | 0.88 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378083 | 0.88 | TDP1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL14159597 | 0.87 | TDP1 (0.71) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21841844 | 0.87 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159762-A1 | NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION | REVVITY HEALTH SCIENCES, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230159762-A1 | NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION | REVVITY HEALTH SCIENCES, INC. | 2023-05-25 | — | — | US | disclosed |
| US-11549017-B2 | NIR to SWIR fluorescent compounds for imaging and detection | PERKINELMER HEALTH SCIENCES, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20220317119-A1 | PARTICLE-BASED IMMUNOASSAY USING A PEGYLATED ANALYTE-SPECIFIC BINDING AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 2022-10-06 | — | — | US | disclosed |
| US-10995004-B2 | Method for functionalizing carbon nanoparticles and compositions | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-05-04 | — | — | US | disclosed |
| US-20200207627-A1 | METHOD FOR FUNCTIONALIZING CARBON NANOPARTICLES AND COMPOSITIONS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2020-07-02 | — | — | US | disclosed |
| US-20190346432-A1 | IMMUNOASSAY USING AT LEAST TWO PEGYLATED ANALYTE-SPECIFIC BINDING AGENTS | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190100654-A1 | NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION | REVVITY HEALTH SCIENCES, INC. | 2019-04-04 | — | — | US | disclosed |
| US-20180172680-A1 | PARTICLE-BASED IMMUNOASSAY USING A PEGYLATED ANALYTE-SPECIFIC BINDING AGENT | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2018-06-21 | — | — | US | disclosed |
| US-20150232616-A1 | HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS | INTEZYNE TECHNOLOGIES, INC. | 2015-08-20 | — | — | US | disclosed |
| US-8426477-B1 | Polymeric micelles for drug delivery | INTEZYNE TECHNOLOGIES, LLC (US) | 2013-04-23 | — | — | US | disclosed |
| US-8299128-B2 | Compositions comprising polymeric micelles for drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| US-20110091534-A1 | COMPOSITIONS COMPRISING POLYMERIC MICELLES FOR DRUG DELIVERY | INTEZYNE TECHNOLOGIES, INC. (US) | 2011-04-21 | — | — | US | disclosed |
| US-7799339-B2 | Copolymer of crosslinkable or crosslinked poly(amino acid block), and a hydrophobic D,L-mixed poly(amino acid) block; an inner core, crosslinked outer core, a hydrophilic shell; improved in vivo circulation time; drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| US-7799339-B2 | Copolymer of crosslinkable or crosslinked poly(amino acid block), and a hydrophobic D,L-mixed poly(amino acid) block; an inner core, crosslinked outer core, a hydrophilic shell; improved in vivo circulation time; drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| US-7638558-B2 | drug loaded micelle of a triblock polymer tert-butylphenylsilylpropene-polyethylene glycol-b-poly(tert-butylaspartic acid-b-polyphenylalanine-copoly( tert-buyltyrosine) has a drug-loaded inner core, a crosslinked outer core, and a hydrophilic shell | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-12-29 | — | — | US | disclosed |
| US-7618944-B2 | Encapsulating in micelle which is a block copolymer containing hydrophilic and hydrophobic blocks | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-11-17 | — | — | US | disclosed |
| US-20080274965-A1 | ENCAPSULATED AMYLOID-BETA PEPTIDES | INTEZYNE TECHNOLOGIES, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080274173-A1 | Copolymer of crosslinkable or crosslinked poly(amino acid block), and a hydrophobic D,L-mixed poly(amino acid) block; an inner core, crosslinked outer core, a hydrophilic shell; improved in vivo circulation time; drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080274173-A1 | Copolymer of crosslinkable or crosslinked poly(amino acid block), and a hydrophobic D,L-mixed poly(amino acid) block; an inner core, crosslinked outer core, a hydrophilic shell; improved in vivo circulation time; drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274965-A1 | ENCAPSULATED AMYLOID-BETA PEPTIDES | IAPP, APP, TTR | TDP1 2067/4885MEN1 227/4885ABL1 4641/4885 |
| US-20200207627-A1 | METHOD FOR FUNCTIONALIZING CARBON NANOPARTICLES AND COMPOSITIONS | TERT, CA13, PCCA | TDP1 3965/4885MEN1 1660/4885ABL1 1064/4885 |
| US-10995004-B2 | Method for functionalizing carbon nanoparticles and compositions | TERT, CA13, PCCA | TDP1 3965/4885MEN1 1660/4885ABL1 1064/4885 |
| US-20110091534-A1 | COMPOSITIONS COMPRISING POLYMERIC MICELLES FOR DRUG DELIVERY | ABCB4, ABCB11, CLTB | TDP1 2472/4885MEN1 921/4885ABL1 1964/4885 |
| US-11549017-B2 | NIR to SWIR fluorescent compounds for imaging and detection | SMARCD1, SMARCE1, SMARCB1 | TDP1 1295/4885MEN1 1886/4885ABL1 4400/4885 |
| US-20080274173-A1 | Copolymer of crosslinkable or crosslinked poly(amino acid block), and a hydrophobic D,L-mixed poly(amino acid) block; an inner core, crosslinked outer core, a hydrophilic shell; improved in vivo circulation time; drug delivery | CLTB, SLC1A5, CLTA | TDP1 3492/4885MEN1 2136/4885ABL1 2607/4885 |
| US-20190100654-A1 | NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION | SMARCD1, SMARCE1, SMARCB1 | TDP1 1295/4885MEN1 1886/4885ABL1 4400/4885 |
| US-20230159762-A1 | NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION | SMARCD1, SMARCE1, SMARCB1 | TDP1 1295/4885MEN1 1886/4885ABL1 4400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.