SCHEMBL922336

SCHEMBL922336

COCc1ccc(C(=O)NCc2ccc(Oc3ccccc3SC)cc2)c(N)n1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.52
LMNA P02545 2/20 0.46
KMT2A Q03164 3/20 0.44
GAA P10253 2/20 0.44
ALDH1A1 P00352 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HTT P42858 1/20 0.42
ATM Q13315 1/20 0.42
MEN1 O00255 1/20 0.41
CARM1 Q86X55 2/20 0.40
PRMT6 Q96LA8 2/20 0.40
MAPK14 Q16539 1/20 0.40
TP53 P04637 1/20 0.39
GLA P06280 1/20 0.39
POLB P06746 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921019 0.91 HPGD (0.53) HPGDLMNAGAAALDH1A1L3MBTL1
SCHEMBL922212 0.89 CARM1 (0.53) HPGDLMNAKMT2AGAAALDH1A1
SCHEMBL920038 0.88 MAPK14 (0.53) HPGDGAAALDH1A1L3MBTL1HTT
SCHEMBL921204 0.88 HPGD (0.54) HPGDLMNAKMT2AGAAALDH1A1
SCHEMBL922047 0.87 HPGD (0.43) HPGDKMT2AGAAALDH1A1L3MBTL1
SCHEMBL919537 0.87 HPGD (0.43) HPGDKMT2AGAAALDH1A1L3MBTL1
SCHEMBL922805 0.87 HPGD (0.43) HPGDLMNAKMT2AGAAALDH1A1
SCHEMBL920439 0.87 MAPK14 (0.53) HPGDLMNAKMT2AGAAALDH1A1
SCHEMBL920788 0.87 HPGD (0.43) HPGDLMNAGAAALDH1A1L3MBTL1
SCHEMBL919997 0.86 MAPK14 (0.50) HPGDLMNAGAAALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885LMNA 4812/4885KMT2A 2469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.