Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558016 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAPTL3MBTL1TDP1MEN1 | |
| SCHEMBL25291048 | 0.78 | MAPT (0.54) | ALDH1A1MAPTL3MBTL1TDP1MEN1 | |
| SCHEMBL27190047 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1TDP1MEN1 | |
| SCHEMBL25251423 | 0.75 | MEN1 (0.45) | ALDH1A1MAPTL3MBTL1TDP1MEN1 | |
| SCHEMBL24715881 | 0.75 | MEN1 (0.62) | ALDH1A1MAPTL3MBTL1TDP1MEN1 | |
| SCHEMBL24716102 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1TDP1MEN1 | |
| SCHEMBL16459386 | 0.71 | TOP2A (0.42) | ALDH1A1MAPTL3MBTL1TDP1MEN1 | |
| SCHEMBL28859500 | 0.71 | IKBKB (0.53) | ALDH1A1L3MBTL1MEN1KMT2ATOP1 | |
| SCHEMBL28868 | 0.71 | IKBKB (0.53) | ALDH1A1L3MBTL1MEN1KMT2ATOP1 | |
| Benzene SCHEMBL28095234 | 0.71 | IKBKB (0.53) | ALDH1A1L3MBTL1MEN1KMT2ATOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994003433-A1 | BIOLOGICAL APPLICATIONS OF ALKALOIDS DERIVED FROM THE TUNICATE EUDISTOMA sp. | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-02-17 | — | — | WO | claimed |
| US-5432172-A | Biological applications of alkaloids derived from the tunicate Eudistoma sp. | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1995-07-11 | — | — | US | disclosed |
| WO-1994003433-A1 | BIOLOGICAL APPLICATIONS OF ALKALOIDS DERIVED FROM THE TUNICATE EUDISTOMA sp. | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-02-17 | — | — | WO | disclosed |