Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4865525 | 0.87 | MEN1 (0.57) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL22120364 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL27190047 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL24716102 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL31295744 | 0.79 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL15712753 | 0.79 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL9224112 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL6537575 | 0.77 | KDM4E (0.63) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL6538214 | 0.76 | MAPT (0.77) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL22120229 | 0.76 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218542-A | Chloro-4,7-phenylbenzene-1,10 phenanthrolines of a kind of 2,9-bis- | DING YUQIN | 2016-01-06 | — | — | CN | claimed |
| US-20240148744-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | ZOETIS LLC | 2024-05-09 | — | — | US | disclosed |
| EP-4291555-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-116806218-A | Sulfonamide and its use for the treatment of parasitic helminth infections and diseases | 新基公司 | 2023-09-26 | — | — | CN | disclosed |
| WO-2022173727-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-08-18 | — | — | WO | disclosed |
| CN-109796403-A | Quinoline derivatives and preparation method thereof | 安徽师范大学 | 2019-05-24 | — | — | CN | disclosed |
| CN-105218542-A | Chloro-4,7-phenylbenzene-1,10 phenanthrolines of a kind of 2,9-bis- | DING YUQIN | 2016-01-06 | — | — | CN | disclosed |
| EP-1423691-A1 | FLUORESCENCE BASED OXYGEN SENSOR SYSTEMS | 3M Innovative Properties Company (US) | 2004-06-02 | — | — | EP | disclosed |
| US-6664111-B2 | The detector is a solid polymeric matrix, e.g., siloxane, modified by a luminescent platinum group metal phenanthroline chelate complex which is quenchable by oxygen; blood and tissue samples; medical diagnosis; compact; lightweight | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-16 | — | — | US | disclosed |
| US-20030099574-A1 | Fluorescence based oxygen sensor systems | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-29 | — | — | US | disclosed |
| WO-2003019179-A1 | FLUORESCENCE BASED OXYGEN SENSOR SYSTEMS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240148744-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | ARSA, MRPS2, SULT2A1 | ALDH1A1 1470/4885MEN1 2604/4885KMT2A 1323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.