Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15300319 | 0.88 | THRB (0.47) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL9062495 | 0.85 | THRB (0.44) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL5981322 | 0.82 | THRB (0.48) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL810800 | 0.77 | THRB (0.47) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL673335 | 0.77 | THRB (0.50) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL31462126 | 0.75 | TSHR (0.57) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL28405795 | 0.75 | TSHR (0.44) | THRBTSHRALDH1A1TDP1POLB | |
| Urea SCHEMBL7101033 | 0.75 | THRB (0.48) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL9322704 | 0.75 | THRB (0.53) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL9322711 | 0.75 | THRB (0.53) | THRBTSHRALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449729-A | Vinyl monomer and crosslinking agent and acrylates with styrene | BAUSCH & LOMB INCORPORATED (US) | 1995-09-12 | — | — | US | disclosed |