Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322711 | 1.00 | THRB (0.53) | THRBTSHRADORA3NR1I2PGR | |
| SCHEMBL15062349 | 0.89 | TSHR (0.58) | THRBTSHRADORA3NR1I2PGR | |
| SCHEMBL22444842 | 0.87 | TSHR (0.61) | THRBTSHRADORA3NR1I2PGR | |
| SCHEMBL6437341 | 0.86 | TSHR (0.64) | THRBTSHRADORA3NR1I2PGR | |
| SCHEMBL6437338 | 0.86 | TSHR (0.64) | THRBTSHRADORA3NR1I2PGR | |
| SCHEMBL14844476 | 0.86 | ADORA3 (0.44) | TSHRADORA3NR1I2PGRPTGS2 | |
| SCHEMBL14844478 | 0.86 | ADORA3 (0.44) | TSHRADORA3NR1I2PGRPTGS2 | |
| SCHEMBL808520 | 0.84 | ADORA3 (0.41) | THRBTSHRADORA3NR1I2PGR | |
| SCHEMBL808519 | 0.84 | ADORA3 (0.41) | THRBTSHRADORA3NR1I2PGR | |
| SCHEMBL14992875 | 0.84 | ADORA3 (0.41) | THRBTSHRADORA3NR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220652-B1 | Method for manufacturing phase gratings of a combination pattern-refraction modification type | KURARAY CO (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-4777116-A | RADIATION OF A MASKED THIN FILM OF A (METH)ACRYLATE POLYMER AND REACTIVE AROMATIC ALDEHYDE AND KETONE | KURARAY CO., LTD. (JP) | 1988-10-11 | — | — | US | disclosed |
| EP-0220652-A2 | Method for manufacturing phase gratings of a combination pattern-refraction modification type | Kuraray Co., Ltd. (JP) | 1987-05-06 | — | — | EP | disclosed |