Methacrylic Acid

Methacrylic Acid

SCHEMBL9224280

C=C(C)C(=O)O.C=C(C)C(=O)O.CCN(CCCO)CCCO

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.40
ALDH1A1 P00352 3/20 0.39
KDM5A P29375 1/20 0.37
KDM4C Q9H3R0 1/20 0.37
ARG1 P05089 1/20 0.35
ARG2 P78540 1/20 0.35
CYP1A2 P05177 3/20 0.33
CHRM2 P08172 2/20 0.33
CHRM1 P11229 2/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
DRD1 P21728 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRM1 P35372 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
KCNH2 Q12809 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL11722830 0.96 PAOX (0.43) PAOXALDH1A1KDM5AKDM4CCYP1A2
Methacrylic Acid SCHEMBL43870 0.88 CYP1A2 (0.44) PAOXALDH1A1KDM5AKDM4CARG1
Methacrylic Acid SCHEMBL344337 0.88 CYP1A2 (0.44) PAOXALDH1A1KDM5AKDM4CARG1
Diethylaminoethanol SCHEMBL11695020 0.83 CYP1A2 (0.39) PAOXALDH1A1ARG1ARG2CYP1A2
Methacrylic Acid SCHEMBL1146682 0.80 CHRM2 (0.38) PAOXALDH1A1CHRM2CHRM1KDM4E
SCHEMBL465303 0.80 HSD17B10 (0.44) PAOXALDH1A1KDM5AKDM4CARG1
Methacrylic Acid SCHEMBL9221834 0.79 LSS (0.35) KDM5AKDM4CKMT2AMEN1
Methacrylic Acid SCHEMBL9138338 0.78 KDM5A (0.41) ALDH1A1KDM5AKDM4CCYP1A2CHRM2
Methacrylic Acid SCHEMBL658460 0.78 GPR84 (0.43) ALDH1A1HSD17B10KDM4ELMNAKMT2A
Methacrylic Acid SCHEMBL18139380 0.78 GPR84 (0.43) ALDH1A1HSD17B10KDM4ELMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995004305-A1 PHOTOSENSITIVE FLUORINATED POLY(AMIC ACID) AMINOACRYLATE SALT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-02-09 WO disclosed