Methacrylic Acid

Methacrylic Acid

SCHEMBL344337

C=C(C)C(=O)O.CCN(CCO)CCO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ARG1 P05089 1/20 0.40
ARG2 P78540 1/20 0.40
PAOX Q6QHF9 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PNP P00491 1/20 0.33
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL43870 1.00 CYP1A2 (0.44) CYP1A2CYP2C9HPGDMAPK1HIF1A
Diethylaminoethanol SCHEMBL11695020 0.96 CYP1A2 (0.39) CYP1A2CYP2C9HPGDMAPK1HIF1A
Trolamine SCHEMBL44442 0.89 MAPT (0.37) CYP1A2CYP2C9HPGDMAPK1HIF1A
Trolamine SCHEMBL345855 0.89 MAPT (0.37) CYP1A2CYP2C9HPGDMAPK1HIF1A
Trolamine SCHEMBL43636 0.89 MAPT (0.37) CYP1A2CYP2C9HPGDMAPK1HIF1A
Methacrylic Acid SCHEMBL9224280 0.88 PAOX (0.40) CYP1A2CYP2C9HPGDMAPK1HIF1A
Acetic Acid SCHEMBL11209916 0.86 CYP1A2 (0.50) CYP1A2CYP2C9HPGDMAPK1HIF1A
Methacrylic Acid SCHEMBL9222623 0.85 CA12 (0.35) CYP1A2CYP2C9HPGDMAPK1HIF1A
Methacrylic Acid SCHEMBL1146682 0.84 CHRM2 (0.38) PAOXALDH1A1KDM4EMAPTCHRM2
Methacrylic Acid SCHEMBL11722830 0.83 PAOX (0.43) CYP1A2PAOXALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024096019-A1 DENTAL ADHESIVE COMPOSITION クラレノリタケデンタル株式会社 2024-05-10 WO disclosed
EP-4364718-A1 DENTAL CURABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2024-05-08 EP disclosed
EP-2979679-B1 CURABLE COMPOSITION FOR DENTAL USE KURARAY NORITAKE DENTAL INC (JP) 2023-11-29 EP disclosed
US-20230049373-A1 PASTE-LIKE COMPOSITION FOR DENTAL USE, AND METHOD FOR PRODUCING THE SAME KURARAY NORITAKE DENTAL INC. (JP) 2023-02-16 US disclosed
US-11173100-B2 Multi-part dental cement KURARAY NORITAKE DENTAL INC. (JP) 2021-11-16 US disclosed
EP-3530258-B1 MULTI-PACK TYPE DENTAL CEMENT KURARAY NORITAKE DENTAL INC (JP) 2021-08-18 EP disclosed
US-20200155421-A1 TWO-PASTE DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2020-05-21 US disclosed
EP-3646847-A1 TWO-PASTE TYPE DENTAL CURABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2020-05-06 EP disclosed
EP-2226060-B1 CEMENT FOR DENTAL APPLICATIONS KURARAY NORITAKE DENTAL INC (JP) 2020-03-04 EP disclosed
US-20190262240-A1 MULTI-PART DENTAL CEMENT KURARAY NORITAKE DENTAL INC. (JP) 2019-08-29 US disclosed
EP-2979679-A1 CURABLE COMPOSITION FOR DENTAL USE Kuraray Noritake Dental Inc. (JP) 2016-02-03 EP disclosed
US-9125802-B2 Dental curable composition KURARAY NORITAKE DENTAL INC. (JP) 2015-09-08 US disclosed
EP-2656831-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2013-10-30 EP disclosed
US-20130274426-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2013-10-17 US disclosed
US-8552088-B2 Cement for dental applications KURARAY NORITAKE DENTAL INC. (JP) 2013-10-08 US disclosed
US-8545225-B2 Redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2013-10-01 US disclosed
EP-2409997-A1 REDOX-CURING TYPE COMPOSITION Kuraray Medical Inc. (JP) 2012-01-25 EP disclosed
US-20120016094-A1 REDOX-CURING TYPE COMPOSITION KURARAY MEDICAL INC. (JP) 2012-01-19 US disclosed
US-20100267856-A1 CEMENT FOR DENTAL APPLICATIONS KURARAY MEDICAL INC. (JP) 2010-10-21 US disclosed
EP-2226060-A1 CEMENT FOR DENTAL APPLICATIONS Kuraray Medical Inc. (JP) 2010-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190262240-A1 MULTI-PART DENTAL CEMENT ASH2L, CAD, SETDB1 CYP1A2 1043/4885CYP2C9 2722/4885HPGD 2284/4885
US-11173100-B2 Multi-part dental cement ASH2L, CAD, SETDB1 CYP1A2 1043/4885CYP2C9 2722/4885HPGD 2284/4885
US-20130274426-A1 DENTAL CURABLE COMPOSITION BAZ2B, BRPF3, SHH CYP1A2 1304/4885CYP2C9 1189/4885HPGD 1237/4885
US-20200155421-A1 TWO-PASTE DENTAL CURABLE COMPOSITION CAD, DNMT3A, DNMT3B CYP1A2 4354/4885CYP2C9 4230/4885HPGD 2624/4885
US-20230049373-A1 PASTE-LIKE COMPOSITION FOR DENTAL USE, AND METHOD FOR PRODUCING THE SAME PFN1, XRN2, FLNA CYP1A2 2947/4885CYP2C9 3238/4885HPGD 3548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.