Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707885 | 0.74 | ALDH1A1 (0.67) | KDM4EALDH1A1MEN1POLBGAA | |
| SCHEMBL9224311 | 0.66 | HDAC3 (0.51) | KDM4EALDH1A1MEN1POLBGAA | |
| SCHEMBL5804362 | 0.64 | KDM4E (0.68) | KDM4EALDH1A1MEN1POLBGAA | |
| SCHEMBL11792241 | 0.63 | ALDH1A1 (0.67) | KDM4EALDH1A1MEN1POLBGAA | |
| SCHEMBL11127980 | 0.62 | ALDH1A1 (1.00) | KDM4EALDH1A1MEN1POLBGAA | |
| SCHEMBL1698928 | 0.62 | ALDH1A1 (0.64) | KDM4EALDH1A1MEN1POLBGAA | |
| SCHEMBL29405336 | 0.62 | ALDH1A1 (0.64) | KDM4EALDH1A1MEN1POLBGAA | |
| SCHEMBL4004859 | 0.62 | TDP1 (0.64) | KDM4EALDH1A1MEN1POLBGAA | |
| SCHEMBL3338265 | 0.60 | PRKCI (0.69) | KDM4EALDH1A1MEN1POLBGAA | |
| SCHEMBL29834174 | 0.60 | PRKCI (0.69) | KDM4EALDH1A1MEN1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7118262-A | — | — | None | — | — | JP | disclosed |
| JP-H07118262-A | NEW 1,2-DITHIOL-3-THIONE DERIVATIVE | MITSUI TOATSU CHEM INC | 1995-05-09 | — | — | JP | disclosed |