Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | THRB | P10828 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | G6PD | P11413 | 1/20 | 0.68 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6128132 | 0.88 | KDM4E (0.61) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL11127980 | 0.82 | ALDH1A1 (1.00) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL10177661 | 0.81 | SLC6A4 (0.53) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL21494243 | 0.80 | RIPK1 (0.50) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL13262507 | 0.79 | SLC6A4 (0.59) | ALDH1A1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL364672 | 0.78 | ESR1 (0.53) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL29707885 | 0.78 | ALDH1A1 (0.67) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL11792241 | 0.78 | ALDH1A1 (0.67) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL6450413 | 0.78 | ALDH1A1 (0.74) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL1616373 | 0.78 | HIF1A (0.54) | MEN1MAPTKMT2ACYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903239-B2 | Fluorinated benzaldehydes | BAYER CHEMICAL AKTIENGESELLSCHAFT (DE) | 2005-06-07 | — | — | US | claimed |
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | claimed |
| US-20040133043-A1 | Fluorinated benzaldehydes | LANXESS DEUTSCHLAND GMBH (DE) | 2004-07-08 | — | — | US | claimed |
| EP-1431279-A2 | Fluoride containing aromatic compounds | Bayer Chemicals AG (DE) | 2004-06-23 | — | — | EP | claimed |
| EP-1428814-A1 | Fluorine containing benzaldehydes | Bayer Chemicals AG (DE) | 2004-06-16 | — | — | EP | claimed |
| US-4378231-A | Motor fuel | PHILLIPS PETROLEUM COMPANY (US) | 1983-03-29 | — | — | US | claimed |
| US-9296711-B2 | Substituted isoxazole amide compounds as inhibitors of stearoyl-CoA desaturase 1 (SCD1) | HOFFMAN-LA ROCHE INC. (US) | 2016-03-29 | — | — | US | disclosed |
| US-20150307463-A1 | SUBSTITUTED ISOXAZOLE AMIDE COMPOUNDS AS INHIBITORS OF STEAROYL-COA DESATURASE 1 (SCD1) | HOFFMANN-LA ROCHE INC. | 2015-10-29 | — | — | US | disclosed |
| EP-2925751-A1 | SUBSTITUTED ISOXAZOLE AMIDE COMPOUNDS AS INHIBITORS OF STEAROYL-COA DESATURASE 1 (SCD1) | F. Hoffmann-La Roche AG (CH) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014086704-A1 | SUBSTITUTED ISOXAZOLE AMIDE COMPOUNDS AS INHIBITORS OF STEAROYL-COA DESATURASE 1 (SCD1) | F. HOFFMANN-LA ROCHE AG (CH) | 2014-06-12 | — | — | WO | disclosed |
| WO-2006076020-A2 | FUEL COMPOSITIONS AND METHODS THEREOF | FERNANDES JOSEPH B (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20050229479-A1 | Fuel compositions and methods thereof | ETANE USA, L.L.C. | 2005-10-20 | — | — | US | disclosed |
| US-6903239-B2 | Fluorinated benzaldehydes | BAYER CHEMICAL AKTIENGESELLSCHAFT (DE) | 2005-06-07 | — | — | US | disclosed |
| EP-1428814-A1 | Fluorine containing benzaldehydes | Bayer Chemicals AG (DE) | 2004-06-16 | — | — | EP | disclosed |
| EP-0750607-B1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |
| EP-0750607-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | Knoll AG (DE) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995023127-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1995-08-31 | — | — | WO | disclosed |
| US-5118325-A | Internal combustion engines | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| US-4378231-A | Motor fuel | PHILLIPS PETROLEUM COMPANY (US) | 1983-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307463-A1 | SUBSTITUTED ISOXAZOLE AMIDE COMPOUNDS AS INHIBITORS OF STEAROYL-COA DESATURASE 1 (SCD1) | SCD, SCD5, CPT1A | KDM4E 797/4885MEN1 4469/4885ALDH1A1 245/4885 |
| US-20040133043-A1 | Fluorinated benzaldehydes | PFAS, FIP1L1, AFF2 | KDM4E 1421/4885MEN1 1248/4885ALDH1A1 25/4885 |
| US-20040171864-A1 | Fluorinated aromatics | AFF1, AFF2, AFF4 | KDM4E 585/4885MEN1 2249/4885ALDH1A1 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.