Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13199954 | 0.75 | NPC1 (0.47) | MEN1KMT2AALDH1A1POLBNPSR1 | |
| SCHEMBL1629546 | 0.73 | MEN1 (0.44) | MEN1KMT2AALDH1A1POLBNPSR1 | |
| SCHEMBL6061823 | 0.70 | CYP11B1 (0.46) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL6061825 | 0.70 | CYP11B1 (0.46) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL9602931 | 0.70 | MEN1 (0.41) | MEN1KMT2AALDH1A1POLBNPSR1 | |
| SCHEMBL30634249 | 0.69 | NPC1 (0.50) | MEN1KMT2AALDH1A1POLBGAA | |
| SCHEMBL18486629 | 0.69 | MEN1 (0.61) | MEN1KMT2AALDH1A1POLBNPSR1 | |
| SCHEMBL13199982 | 0.68 | NEK2 (0.42) | MEN1KMT2AALDH1A1NPSR1KDM4E | |
| SCHEMBL8661673 | 0.67 | NR1I2 (0.53) | MEN1KMT2AALDH1A1POLBNPSR1 | |
| SCHEMBL5002639 | 0.67 | NR1I2 (0.53) | MEN1KMT2AALDH1A1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642521-A1 | THIO-SUBSTITUTED NITROGEN-CONTAINING HETEROCYCLIC PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS (US) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024500-A1 | THIO-SUBSTITUTED NITROGEN-CONTAINING HETEROCYCLIC PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | THE PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |