Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 4/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 8/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.38 |
| ▸ | PTGFR | P43088 | 3/20 | 0.38 |
| ▸ | PTGIR | P43119 | 3/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.37 |
| ▸ | ACE | P12821 | 3/20 | 0.37 |
| ▸ | F7 | P08709 | 2/20 | 0.36 |
| ▸ | F3 | P13726 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223402 | 0.92 | XIAP (0.38) | XIAPGHSRAGTR1PTGER1PTGER3 | |
| SCHEMBL9216016 | 0.92 | XIAP (0.37) | XIAPGHSRAGTR1PTGER1PTGER3 | |
| SCHEMBL9221294 | 0.91 | XIAP (0.37) | XIAPGHSRAGTR1PTGER1PTGER3 | |
| SCHEMBL9222553 | 0.91 | XIAP (0.37) | XIAPGHSRAGTR1PTGER1PTGER3 | |
| SCHEMBL9218242 | 0.91 | XIAP (0.45) | XIAPGHSRAGTR1PTGER1PTGER3 | |
| SCHEMBL9221625 | 0.90 | XIAP (0.43) | XIAPAGTR1PTGER1PTGER3PTGER2 | |
| SCHEMBL9223271 | 0.89 | GHSR (0.50) | XIAPGHSRAGTR1PTGER1PTGER3 | |
| SCHEMBL9101307 | 0.87 | GHSR (0.53) | XIAPGHSRAGTR1PTGER1PTGER3 | |
| SCHEMBL7791693 | 0.85 | GHSR (0.56) | XIAPGHSRAGTR1MMEACE | |
| SCHEMBL9221689 | 0.85 | XIAP (0.43) | XIAPGHSRAGTR1PTGER1PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003289-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | claimed |