Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.36 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 8/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.36 |
| ▸ | PTGFR | P43088 | 3/20 | 0.36 |
| ▸ | PTGIR | P43119 | 3/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223402 | 0.93 | XIAP (0.38) | XIAPAGTR1GHSRPTGER1PTGER3 | |
| SCHEMBL9216442 | 0.92 | GHSR (0.39) | XIAPAGTR1GHSRFPR2FPR1 | |
| SCHEMBL9224345 | 0.92 | XIAP (0.43) | XIAPAGTR1GHSRPTGER1PTGER3 | |
| SCHEMBL9289634 | 0.91 | AGTR2 (0.40) | AGTR1PTGER1PTGER3PTGER4PTGER2 | |
| SCHEMBL9222553 | 0.91 | XIAP (0.37) | XIAPAGTR1GHSRPTGER1PTGER3 | |
| SCHEMBL9221294 | 0.91 | XIAP (0.37) | XIAPAGTR1GHSRPTGER1PTGER3 | |
| SCHEMBL9224430 | 0.90 | GHSR (0.45) | XIAPAGTR1GHSRPTGER1PTGER3 | |
| SCHEMBL9105761 | 0.89 | GHSR (0.44) | XIAPAGTR1GHSRPTGER1PTGER3 | |
| SCHEMBL7792292 | 0.86 | GHSR (0.51) | XIAPAGTR1GHSRFPR2FPR1 | |
| SCHEMBL9220967 | 0.86 | GHSR (0.46) | XIAPGHSRPTGER1PTGER3PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003289-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | claimed |