Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 9/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403161 | 0.80 | HRH1 (0.86) | HRH1HTR2AMAOASLC7A5TAAR1 | |
| SCHEMBL8157930 | 0.79 | HRH1 (0.38) | HRH1HTR2ATAAR1CYP2C19 | |
| SCHEMBL1024126 | 0.79 | SIGMAR1 (0.44) | HRH1HTR2A | |
| SCHEMBL3020787 | 0.78 | HRH1 (0.40) | HRH1HTR2ATAAR1TSHRCYP2C19 | |
| SCHEMBL1204774 | 0.78 | HRH1 (0.83) | HRH1HTR2AMAOASLC7A5TAAR1 | |
| SCHEMBL2836377 | 0.78 | HRH1 (0.83) | HRH1HTR2AMAOASLC7A5TAAR1 | |
| SCHEMBL2849801 | 0.78 | HRH1 (0.83) | HRH1HTR2AMAOASLC7A5TAAR1 | |
| SCHEMBL11328616 | 0.78 | HRH1 (0.83) | HRH1HTR2AMAOASLC7A5TAAR1 | |
| SCHEMBL5089222 | 0.78 | HRH1 (0.83) | HRH1HTR2AMAOASLC7A5TAAR1 | |
| SCHEMBL29060377 | 0.78 | HRH1 (0.83) | HRH1HTR2AMAOASLC7A5TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470834-A | Metalloproteinase enzyme inhibitors for arthritis, rheumatism and cancers | FLORIDA STATE UNIVERSITY (US) | 1995-11-28 | — | — | US | disclosed |