Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 9/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | USP2 | O75604 | 8/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197546 | 0.86 | DYRK1A (0.55) | CLK4MAPK1DYRK1AMAP4K4FAAH | |
| SCHEMBL926786 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNADYRK1AKDM4ENPC1 | |
| SCHEMBL29475990 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNADYRK1AKDM4ENPC1 | |
| SCHEMBL28048555 | 0.80 | DYRK1A (0.72) | CLK4ALDH1A1DYRK1ANPC1RAB9A | |
| SCHEMBL9224654 | 0.80 | DYRK1A (0.55) | CLK4ALDH1A1TSHRDYRK1AMAP4K4 | |
| SCHEMBL592989 | 0.79 | DYRK1A (0.62) | ALDH1A1DYRK1AMAP4K4KDM4ENPC1 | |
| SCHEMBL29375136 | 0.79 | DYRK1A (0.62) | ALDH1A1DYRK1AMAP4K4KDM4ENPC1 | |
| SCHEMBL9222743 | 0.76 | DYRK1A (0.55) | CLK4DYRK1AMAP4K4NOTUMCLK1 | |
| SCHEMBL3476126 | 0.76 | KLK3 (0.56) | DYRK1ATDP1PDGFRBPDGFRAMEN1 | |
| SCHEMBL28331613 | 0.75 | PIK3R1 (0.55) | CLK4CYP1A2CYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422237-A | Methine compound and silver halide photographic material comprising the same | FUJI PHOTO FILM CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |