Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29475990 | 0.86 | ALDH1A1 (0.48) | DYRK1ACLK1NPC1CASP3RAB9A | |
| SCHEMBL926786 | 0.86 | ALDH1A1 (0.48) | DYRK1ACLK1NPC1CASP3RAB9A | |
| SCHEMBL9224437 | 0.86 | CLK4 (0.52) | DYRK1ACLK1MAP4K4PDGFRBPDGFRA | |
| SCHEMBL28048555 | 0.84 | DYRK1A (0.72) | DYRK1ACLK1FASNCLK4NPC1 | |
| SCHEMBL10337032 | 0.81 | DYRK1A (0.60) | DYRK1ACLK1FASNENPP3CLK4 | |
| SCHEMBL3476126 | 0.80 | KLK3 (0.56) | DYRK1ACLK1PDGFRBPDGFRA | |
| SCHEMBL29375136 | 0.79 | DYRK1A (0.62) | DYRK1AMAP4K4FASNNPC1RAB9A | |
| SCHEMBL592989 | 0.79 | DYRK1A (0.62) | DYRK1AMAP4K4FASNNPC1RAB9A | |
| SCHEMBL31637831 | 0.78 | NPC1 (0.50) | CLK1NPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL9440539 | 0.78 | CYP11B1 (0.43) | DYRK1ACLK1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103739565-B | Method for synthesizing medicament intermediate benzoxazine ketone derivative | 2ND AFFILIATED HOSPITAL & YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY | 2015-06-03 | — | — | CN | disclosed |
| CN-103739565-A | Method for synthesizing medicament intermediate benzoxazine ketone derivative | 2ND AFFILIATED HOSPITAL & YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY | 2014-04-23 | — | — | CN | disclosed |
| EP-0532798-B1 | An electroluminescent element | ASAHI CHEMICAL IND (JP) | 1995-12-06 | — | — | EP | disclosed |
| EP-0532798-A1 | An electroluminescent element | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1993-03-24 | — | — | EP | disclosed |