Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670166 | 0.83 | DNMT1 (0.42) | WDR5CES1DNMT1RORARORC | |
| SCHEMBL132989 | 0.82 | WDR5 (0.44) | NPSR1WDR5POLBCES1DNMT1 | |
| SCHEMBL29382484 | 0.82 | WDR5 (0.44) | NPSR1WDR5POLBCES1DNMT1 | |
| SCHEMBL7029202 | 0.80 | MAPT (0.37) | WDR5POLBAPOBEC3ACASP6KMT2A | |
| SCHEMBL29559059 | 0.80 | MAPT (0.37) | WDR5POLBAPOBEC3ACASP6KMT2A | |
| SCHEMBL7636752 | 0.75 | NSD2 (0.43) | KMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL4403131 | 0.74 | MAPT (0.43) | NPSR1WDR5POLBKMT2ACTDSP1 | |
| SCHEMBL7025867 | 0.74 | KMT2A (0.42) | NPSR1WDR5POLBAPOBEC3ACASP6 | |
| SCHEMBL12336891 | 0.74 | MAPT (0.43) | NPSR1WDR5POLBKMT2ACTDSP1 | |
| SCHEMBL6053369 | 0.74 | WDR5 (0.38) | NPSR1WDR5POLBCES1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503884-B1 | Optically active diphenylphosphino-binaphtyl compounds and catalytic transition metal complexes thereof | TAKASAGO PERFUMERY CO LTD (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5231202-A | OPTICALLY ACTIVE TERTIARY PHOSPHINE COMPOUND AND TRANSITION METAL COMPLEX USING THE SAME AS LIGAND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-07-27 | — | — | US | disclosed |
| EP-0503884-A1 | Optically active diphenylphosphino-binaphtyl compounds and catalytic transition metal complexes thereof | Takasago International Corporation (JP) | 1992-09-16 | — | — | EP | disclosed |