Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132989 | 0.90 | WDR5 (0.44) | POLBMAPTWDR5KDM4EHSD17B10 | |
| SCHEMBL29382484 | 0.90 | WDR5 (0.44) | POLBMAPTWDR5KDM4EHSD17B10 | |
| SCHEMBL31296445 | 0.88 | MAPT (0.46) | KMT2APOLBCTDSP1MAPTMEN1 | |
| SCHEMBL7118382 | 0.88 | HSP90AA1 (0.42) | KMT2APOLBAPOBEC3ACASP6CTDSP1 | |
| SCHEMBL7809844 | 0.87 | KMT2A (0.43) | KMT2APOLBAPOBEC3ACASP6CTDSP1 | |
| SCHEMBL7808240 | 0.84 | MAPT (0.51) | KMT2APOLBAPOBEC3ACASP6CTDSP1 | |
| SCHEMBL7591355 | 0.84 | MAPT (0.43) | KMT2APOLBHSP90AA1HSP90AB1MAPT | |
| SCHEMBL12336891 | 0.81 | MAPT (0.43) | KMT2APOLBCTDSP1MAPTMEN1 | |
| SCHEMBL4403131 | 0.81 | MAPT (0.43) | KMT2APOLBCTDSP1MAPTMEN1 | |
| SCHEMBL6053369 | 0.81 | WDR5 (0.38) | POLBHSP90AA1HSP90AB1MAPTWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041077-B1 | Phosphine derivative and polymer thereof and transition metal complex comprising the same | TAKASAGO PERFUMERY CO LTD (JP) | 2003-11-05 | — | — | EP | disclosed |
| EP-0684249-B1 | Phosphine compounds, complexes containing the phosphine compounds as ligands, and process for producing optically active aldehydes using the phosphine compounds or complexes | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-19 | — | — | EP | disclosed |
| EP-0864577-B1 | Optically active phosphine derivative having at least two vinyl groups, polymer produced using the same as monomer and transition metal complexes of these | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-05 | — | — | EP | disclosed |
| EP-0877029-B1 | Optically active phosphine derivative having vinyl group, polymer produced using the same as monomer and transition metal complexes of these | TAKASAGO PERFUMERY CO LTD (JP) | 2002-12-11 | — | — | EP | disclosed |
| US-6465594-B1 | POLYMERIZING VINYL-SUBSTITUTED BIS(DIARYLPHOSPHINO) BINAPHTHALENE COMPOUNDS OR COMPLEX, ESPECIALLY WITH A STYRENE AND DIVINYLBENZENE; USED TO CATALYZE ASYMMETRIC HYDROGENATION TO PRODUCE AN OPTICALLY ACTIVE AMINO ACID COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-10-15 | — | — | US | disclosed |
| EP-0684230-B1 | 4- (R)-1'-formylethyl azetidin-2-one derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-6248848-B1 | Optically active phosphine derivative having at least two vinyl groups, polymer produced using the same as monomer, and transition metal complexes of these | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-06-19 | — | — | US | disclosed |
| US-6143834-A | Optically active phosphine derivative having at least two vinyl groups, polymer produced using the same as monomer, and transition metal complexes of these | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-1041077-A2 | Phosphine derivative and polymer thereof and transition metal complex comprising the same | Takasago International Corporation (JP) | 2000-10-04 | — | — | EP | disclosed |
| EP-0614903-B1 | Process for producing optically active aldehydes using transition metal-phosphine complexes, and process for producing intermediates for carbapenem antibiotics using the same complexes | TAKASAGO PERFUMERY CO LTD (JP) | 2000-09-20 | — | — | EP | disclosed |
| EP-0864577-A2 | Optically active phosphine derivative having at least two vinyl groups, polymer produced using the same as monomer and transition metal complexes of these | Takasago International Corporation (JP) | 1998-09-16 | — | — | EP | disclosed |
| US-5631345-A | REACTING CARBON MONOXIDE AND UNSATURATED COMPOUND IN PRESENCE OF PALLADIUM-PHOSHINE COMPLEX | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0732350-A2 | Process for producing optically active polyketone | Takasago International Corporation (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5530150-A | HAVING PHOSPHINE AND PHOSPHITE GROUPS IN SAME MOLECULE; CATALYST SELECTIVITY | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0684249-A1 | Phosphine compounds, complexes containing the phosphine compounds as ligands, and process for producing optically active aldehydes using the phosphine compounds or complexes | Takasago International Corporation (JP) | 1995-11-29 | — | — | EP | disclosed |
| EP-0684230-A1 | 4- (R)-1'-formylethyl azetidin-2-one derivatives | Takasago International Corporation (JP) | 1995-11-29 | — | — | EP | disclosed |
| EP-0503884-B1 | Optically active diphenylphosphino-binaphtyl compounds and catalytic transition metal complexes thereof | TAKASAGO PERFUMERY CO LTD (JP) | 1995-07-26 | — | — | EP | disclosed |
| EP-0614903-A2 | Phosphine compounds, complexes containing the phosphine compounds as ligands, process for producing optically active aldehydes using the phosphine compounds, or complexes, and 4-[(R)-1' formylethyl]azetidin-2-one derivatives | Takasago International Corporation (JP) | 1994-09-14 | — | — | EP | disclosed |
| US-5231202-A | OPTICALLY ACTIVE TERTIARY PHOSPHINE COMPOUND AND TRANSITION METAL COMPLEX USING THE SAME AS LIGAND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-07-27 | — | — | US | disclosed |
| EP-0503884-A1 | Optically active diphenylphosphino-binaphtyl compounds and catalytic transition metal complexes thereof | Takasago International Corporation (JP) | 1992-09-16 | — | — | EP | disclosed |