Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223511 | 0.84 | ALOX15 (0.56) | ALOX15HIF1AESR1LMNAALDH1A1 | |
| SCHEMBL15548452 | 0.83 | ALOX15 (0.61) | ALOX15HIF1AESR1ACHEFGFR1 | |
| SCHEMBL9226420 | 0.79 | ALOX15 (0.58) | ALOX15LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL9218416 | 0.79 | ALOX15 (0.58) | ALOX15LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL9223524 | 0.79 | ALOX15 (0.58) | ALOX15LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL9220834 | 0.79 | ALOX15 (0.58) | ALOX15LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL11290650 | 0.78 | ALOX15 (0.52) | ALOX15HIF1AESR1ACHEFGFR1 | |
| SCHEMBL3127157 | 0.78 | ALOX15 (0.59) | ALOX15HIF1AESR1ACHEFGFR1 | |
| SCHEMBL11290671 | 0.77 | ALOX15 (0.48) | ALOX15HIF1AESR1ACHEFGFR1 | |
| SCHEMBL9225477 | 0.76 | ALOX15 (0.51) | ALOX15LMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147174-B1 | DIHYDROXYBENZALDEHYDE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-06-27 | — | — | EP | claimed |
| US-4758591-A | Dialkanoyloxybenzylidene dialkanoate | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-07-19 | — | — | US | claimed |
| EP-0147174-A2 | Dihydroxybenzaldehyde derivatives as anti-inflammatory agents | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-07-03 | — | — | EP | claimed |
| JP-61007234-A | — | — | None | — | — | JP | disclosed |
| EP-0395441-B1 | Treating agent for osteoarthritis | KUREHA CHEMICAL IND CO LTD (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-4997850-A | Alcohol or ester | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0395441-A2 | Treating agent for osteoarthritis | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-10-31 | — | — | EP | disclosed |
| EP-0147174-B1 | DIHYDROXYBENZALDEHYDE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0357092-A1 | Preparation of diacetoxybenzylidene diacetates | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4841097-A | REACTING DIHYDROXYBENZALDEHYDE WITH ALKANOIC ACID ANHYDRIDE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-06-20 | — | — | US | disclosed |
| US-4758591-A | Dialkanoyloxybenzylidene dialkanoate | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-07-19 | — | — | US | disclosed |
| JP-S617234-A | DIALKANOYLOXYBENZYLIDENE DIALKANOATE | KUREHA CHEM IND CO LTD | 1986-01-13 | — | — | JP | disclosed |
| EP-0147174-A2 | Dihydroxybenzaldehyde derivatives as anti-inflammatory agents | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-07-03 | — | — | EP | disclosed |