Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284866 | 0.89 | ADRB2 (0.44) | ALOX15ALDH1A1ADRB2PDE4BKDM4E | |
| SCHEMBL11284384 | 0.84 | SLC22A3 (0.57) | ALOX15HIF1ALMNACYP3A4ALDH1A1 | |
| SCHEMBL11284864 | 0.82 | ADRB2 (0.37) | HIF1AESR1LMNAALDH1A1SLC22A3 | |
| SCHEMBL11145357 | 0.79 | ADRB2 (0.44) | LMNAALDH1A1ADRB2KDM4EMEN1 | |
| SCHEMBL9224683 | 0.77 | ALOX15 (0.54) | ALOX15HIF1AESR1LMNACYP3A4 | |
| SCHEMBL15548452 | 0.77 | ALOX15 (0.61) | ALOX15HIF1AESR1ACHEFGFR1 | |
| SCHEMBL11524503 | 0.73 | SLC22A3 (0.53) | ALOX15HIF1ALMNACYP3A4ALDH1A1 | |
| SCHEMBL11292335 | 0.73 | ALOX15 (0.48) | ALOX15TDP1KMT2AGAA | |
| SCHEMBL11277089 | 0.73 | ALOX15 (0.48) | ALOX15TDP1KMT2AGAA | |
| SCHEMBL23337952 | 0.72 | HIF1A (0.71) | ALOX15HIF1AESR1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |