Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344324 | 0.77 | CYP17A1 (0.51) | CYP17A1OPRM1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL7166658 | 0.75 | CYP17A1 (0.55) | CYP17A1OPRM1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL19383233 | 0.74 | CYP17A1 (0.57) | CYP17A1OPRM1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL28091017 | 0.74 | GAA (0.96) | GAAL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL21104687 | 0.74 | GAA (0.96) | GAAL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL3671016 | 0.74 | GAA (0.96) | GAAL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL3665297 | 0.74 | GAA (0.96) | GAAL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL8160351 | 0.74 | CYP17A1 (0.57) | CYP17A1OPRM1OPRK1OPRL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28720089 | 0.73 | GAA (0.93) | GAAL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL6482657 | 0.73 | CYP1A2 (0.53) | L3MBTL1ALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420348-A | Enzyme inhibitors | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0447116-B1 | Urea derivatives, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMA CO LTD (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5258405-A | Acetyl coenzyme A cholesterol acetyltransferase inhibitors for cardiovascular disorders and atherosclerosis and antilipemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0447116-A1 | Urea derivatives, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |