Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635146 | 0.86 | CDC25B (0.40) | CDC25BKDM4EALDH1A1POLBHPGD | |
| SCHEMBL29082491 | 0.84 | KDM4E (0.56) | CDC25BKDM4EALDH1A1POLBHPGD | |
| SCHEMBL30628896 | 0.84 | KDM4E (0.56) | CDC25BKDM4EALDH1A1POLBHPGD | |
| SCHEMBL16432815 | 0.78 | KDM4E (0.52) | CDC25BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1162404 | 0.77 | CDC25B (0.80) | CDC25BKDM4EALDH1A1POLBHPGD | |
| SCHEMBL13634931 | 0.77 | MAPT (0.36) | CDC25BKDM4EALDH1A1POLBHPGD | |
| SCHEMBL10889935 | 0.75 | CDC25B (0.78) | CDC25BKDM4EALDH1A1POLBHPGD | |
| SCHEMBL3197711 | 0.75 | ALDH1A1 (0.61) | CDC25BKDM4EALDH1A1POLBHPGD | |
| SCHEMBL6916951 | 0.73 | ALDH1A1 (0.59) | CDC25BKDM4EALDH1A1POLBHPGD | |
| SCHEMBL6915569 | 0.73 | ALDH1A1 (0.59) | CDC25BKDM4EALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7149750-A | — | — | None | — | — | JP | disclosed |
| EP-1858836-B1 | ANALOGUES OF THE AZINOMYCINS AS ANTI-TUMOUR AGENTS AND AS PRODRUGS | UNIV BRADFORD (GB) | 2009-11-18 | — | — | EP | disclosed |
| US-20090233966-A1 | Analogues of the Azinomycins as Anti-Tumour Agents and as Prodrugs | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2009-09-17 | — | — | US | disclosed |
| US-20090233966-A1 | Analogues of the Azinomycins as Anti-Tumour Agents and as Prodrugs | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2009-09-17 | — | — | US | disclosed |
| JP-H07149750-A | CARCINOSTATIC AGENT CONTAINING 3-METHOXY-5-METHYLNAPHTHALENE-1-CARBOXYLIC ACID ESTER DERIVATIVE AS ACTIVE INGREDIENT | SAGAMI CHEM RES CENTER | 1995-06-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233966-A1 | Analogues of the Azinomycins as Anti-Tumour Agents and as Prodrugs | CYP1B1, AZI2, ECI1 | CDC25B 366/4885KDM4E 993/4885ALDH1A1 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.