Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225386 | 1.00 | IL6ST (0.49) | IL6STKMT2ACCR5ALDH1A1MEN1 | |
| SCHEMBL9225391 | 1.00 | IL6ST (0.49) | IL6STKMT2ACCR5ALDH1A1MEN1 | |
| SCHEMBL7297353 | 0.86 | IL6ST (0.40) | IL6STKMT2ACCR5ALDH1A1MEN1 | |
| SCHEMBL9216987 | 0.85 | IL6ST (0.55) | IL6STKMT2AALDH1A1MEN1STAT3 | |
| SCHEMBL9216981 | 0.85 | IL6ST (0.55) | IL6STKMT2AALDH1A1MEN1STAT3 | |
| SCHEMBL7268237 | 0.85 | IL6ST (0.55) | IL6STKMT2AALDH1A1MEN1STAT3 | |
| SCHEMBL7268241 | 0.85 | IL6ST (0.55) | IL6STKMT2AALDH1A1MEN1STAT3 | |
| SCHEMBL9739729 | 0.83 | IL6ST (0.59) | IL6STLTA4HSTAT3 | |
| SCHEMBL9739731 | 0.83 | IL6ST (0.59) | IL6STLTA4HSTAT3 | |
| SCHEMBL9217065 | 0.79 | TDP1 (0.49) | IL6STALDH1A1SMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378689-A | Hypotensive agents; administrable by mouth | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |