SCHEMBL9225463

SCHEMBL9225463

C=CC[Si](Cl)(Cl)CCCC#N

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28869458 0.87 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL2101196 0.79 TSHR (0.41) ALDH1A1TSHR
SCHEMBL28492917 0.73 TSHR (0.36) ALDH1A1TSHR
SCHEMBL387076 0.73
SCHEMBL28819146 0.71
SCHEMBL20473670 0.71 TSHR (0.37) ALDH1A1TSHR
SCHEMBL6063886 0.71 TSHR (0.40) ALDH1A1TSHR
SCHEMBL28015912 0.71 ALDH1A1 (0.30) ALDH1A1
SCHEMBL31599238 0.71 TSHR (0.46) ALDH1A1TSHR
SCHEMBL20473659 0.70 TSHR (0.41) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5420323-A Hydrosilation KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1995-05-30 US disclosed